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Open Access Article

Journal of Cell and Molecular Biology Research. 2023; 3: (1) ; 5-8 ; DOI: 10.12208/j.jcmbr.20230002.

Research progress on pharmacological action of songorine
一枝蒿庚素的药理作用研究进展

作者: 刘健, 曹井龙, 薛慧, 李艳楠, 侯文爽, 金成浩 *

黑龙江八一农垦大学生命科学技术学院 黑龙江大庆

*通讯作者: 金成浩,单位:黑龙江八一农垦大学生命科学技术学院 黑龙江大庆;

发布时间: 2023-03-14 总浏览量: 1106

摘要

雪上一枝蒿是我国传统药用植物,用于治疗风湿疼痛、跌打损伤等病症。一枝蒿庚素是从雪上一枝蒿中提取分离出的一种C20-二萜生物碱。药理学研究表明,一枝蒿庚素具有抗炎、抗焦虑、抗肿瘤、抗心律失常及抗心脏衰竭等多种药理作用。本文对近年来一枝蒿庚素药理作用的研究进行综述,以期为一枝蒿庚素的深入研究及临床应用提供理论依据。

关键词: 一枝蒿庚素;二萜生物碱;抗炎;抗癌;药理作用

Abstract

Shortstalkmonkshood root is a traditional medicinal plant used to treat rheumatic pain, injury and other diseases. Songorine is a C20-diterpenoid alkaloid extracted and isolated from shortstalk monkshood root. Pharmacological studies have shown that songorine has anti-inflammatory, anti-anxiety, anti-tumor, anti-arrhythmia and anti-heart failure pharmacological action. In this paper, the pharmacological effects of songorine in recent years were reviewed in order to provide theoretical basis for further research and clinical application of songorine.

Key words: Songorine;diterpenoid alkaloids; anti-inflammatory; anti-tumor; pharmacological action

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引用本文

刘健, 曹井龙, 薛慧, 李艳楠, 侯文爽, 金成浩, 一枝蒿庚素的药理作用研究进展[J]. 细胞与分子生物学研究, 2023; 3: (1) : 5-8.